(Test Bank) Understanding Pathophysiology

Huenther, 7

Physiology

Test Bank

7th Edition

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Test Bank for Understanding Pathophysiology, The downloadable file consists of 773 pages, and the total size of the file is 7.92 MB. Purchase now only for highly discounted price.

Author(s): Huenther

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TEST BANK UNDERSTAND ING PATHOPHYSIOLOGY 7TH EDITION BY SUE HUENTHER Test Bank For: Understanding Pat hophysiology 7th Edition By Sue Huenther CONTENTS: PART ONE: BA SIC CONCEPTS OF PATHOPHYSIOLOGY Unit 1: The Cell Chapter 1. Cellular Biology Chapter 2. Genes and Genetic Diseases Chapter 3. Epigenetics and Disease Chapter 4. Altered Cellular and Tissue Biology Chapter 5. Fluids an d Electrolytes, Acids and Bases Unit 2: Mechanisms of Self -Defense Chapter 6. Innate Immunity: Inflammation and Wound Healing Chapter 7. Adaptive Immunity Chapter 8. Alterations in Immunity NEW Chapter 9. Infection and Defects in Mechanisms of Defense Chapter 10. Stress and Disease Unit 3: Cellular Proliferation: Cancer Chapter 11. Biology of Cancer Chapter 12. Cancer Epidemiology Chapter 13. Can cer in Children and Adolescents PART TWO: BODY SYSTEMS AND DISEASES Unit 4: The Neurologic System Chapter 14. Structure and Function of the Neurologic System Chapter 15. Pain, T emperature, Sleep, and Sensory Function Chapter 16. Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function Chapter 17. Disorders of the Central and Peripheral Nervous Systems and Neuromuscular Junction Chapter 18. Alterations of Neurologic Function in Childre n Unit 5: The Endocrine System Chapter 19. Mechanisms of Hormonal Regulation Chapter 20. Alterations of Hormonal Regulation Chapter 21. Obesity and Disorders of Nutrition NEW Unit 6: The Hematologic System Chapter 22. Structure and Function of the Hematologic System Chapter 23. Alterations of Hematologic Function Chapter 24. Alterations of H ematologic Function in Children Unit 7: The Cardiovascular and Lymphatic Systems Chapter 25. Structure and Function of the Cardiovascular and Lymphatic Systems Chapter 26. Alterations of Cardiovascular Function Chapter 27. Alterations of Card iovascular Function in Children Unit 8: The Pulmonary System Chapter 28. Structure and Function of the Pulmonary System Chapter 29. Alterations of Pulmonary Function Chapter 30. Alterations of Pulmonary Function in Child ren Chapter Unit 9: The Renal and Urologic Systems Chapter 31. Structure and Function of the Renal and Urologic Systems Chapter 32. Alterations of Renal and Urinary Tract Function Chapter 33. Alterations of Renal and Uri nary Tract Function in Children Unit 10: The Reproductive Systems Chapter 34. Structure and Function of the Re productive Systems Chapter 35. Alterations of the Female Reproductive System Test Bank For: Understanding Pat hophysiology 7th Edition By Sue Huenther Chapter 36. Alterations of the Male Reproductive System Unit 11: The Digestive System Chapter 37. Structure and Function of the Digestive System Chapter 38. Alterations of Digestive Function Chapter 39. Alterations of Digestive Function in Children Unit 12: The Musculoskeletal and Integumentary Systems Chapter 40. Structure and Function of the Musculoskeletal System Chapter 41. Alterations of Musculoskeletal Function Chapter 42. Alterations of Musculoskeletal Function in Children Chapter 43. Structur e, Function, and Disorders of the Integument Chapter 44. Alterations of the Integument in Children Test Bank For: Understanding Pathophysiology 7th Edition By Sue Huenther Understanding Pathophysiology 7th Edition Test Bank Chapter 1. Cellular Biology Multiple Choice 1. A student is observing a cell under the microscope. It is observed to have supercoiled DNA with histones. Which of the following would also be observed by the student? a. A single circular chromosome b. A nucleus c. Free-floating nuclear material d. No organelles ANS: B The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within its nucleus; thus, the nucleus should be observed. A single circular chromosome is characteristic of prokaryotic cells, which do not have histones. Free-floating nuclear material describes a prokaryotic cell, which would not have a distinct nucleus. Eukaryotic cells have membrane bounded cellular components called organelles. No organelles describes a prokaryotic cell. 2. A nurse is instruct ing the staff about cellular functions. Which cellular function is the nurse describing when an isolated cell absorbs oxygen and uses it to transform nutrients to energy? a. Metabolic absorption b. Communication c. Secretion d. Respiration Test Bank For: Understanding Pathophysiology 7th Edition By Sue Huenther ANS: D The ability of the cell to absorb oxygen refers to the cells function of respiration. The ability of the cell to function within a society of cells refers to its function of communication. The ability of the cell to take in nutrients refers to the cells function of metabolic absorption. The ability of the cell to synthesize new substances and secrete these elsewhere refers to the cells function of secretion. 3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would most of the genetic information be contained? a. Mitochondria b. Ribosome c. Nucleolus d. Nucleus ANS: C The region of the cell that contains genetic material, including a large amount of ribonucleic acid, most of the DNA, and DNA -binding proteins, is the nucleolus. The mitochondria is the site of cellular respiration. The ribosomes are involved in manufacturing of proteins within the cell. The nucleus contains the nucleolus, and it is the nucleolus that contains genetic material. 4. The fluid mosaic model for biologic membranes describes membrane behavior. According to this model, which of the following float singly or as aggregates in the fluid lipid bilayer? a. Peripheral membrane proteins b. Integral membrane proteins Test Bank For: Understanding Pathophysiology 7th Edition By Sue Huenther c. Glycoproteins d. Cell adhesion molecules ANS: B Integral membrane proteins float freely in the fluid lipid bilayer. Peripheral membrane proteins are not embedded in the layer, but reside at the surface. Glycoproteins act as cell surface markers. Cell adhesion molecules are on the outside of the membrane and allow cells to hook together. 5. Which of the following can bind to plasma membrane receptors? a. Oxygen b. Ribosomes c. Amphipathic lipids d. Ligands ANS: D Ligands are specific molecules that can bind with receptors on the cell membrane. Oxygen moves by diffusion; it does not bind to receptors. Ribosomes make proteins and are not involved in binding. Amphipathic lipids are a portion of the cell membrane. 6. A nurse is reviewing a report from a patient with metastatic cancer. What finding would support the diagnosis of metastatic cancer? Alterations in extracellular matrix that include: a. Decreased fibronectin b. Increased collagen c. Decreased elastin Test Bank For: Understanding Pathophysiology 7th Edition By Sue Huenther d. Increased glycoproteins ANS: A Reduced amounts of fibronectin are found in some types of cancerous cells, allowing cancer cells to travel, or metastasize. Collagen provides strength, and its breakdown is associated with osteoarthritis, not cancer. Elastin is found in the lungs and allows tissues to stretch; it is not associated with cancerous cells. Decreased, not increased, glycoproteins are associated with cancerous cells. 7. Which form of cell communication is used to relate to other cells in direct physical contact? a. Cell junction b. Gap junction c. Desmosomes d. Tight junctions ANS: A Cell junctions hold cells together and permit molecules to pass from cell to cell. Gap junctions allow communication from the inside of one cell to the inside of another. Desmosomes are not involved in communication, but allow cells to hold together. Tight junctions are barriers that prevent movement of some substances and leakages of others. 8. Pancreatic beta cells secrete insulin, which inhibits secretion of glucagon from neighboring alpha cells. This action is an example of which of the following signaling types? a. Paracrine b. Autocrine Test Bank For: Understanding Pathophysiology 7th Edition By Sue Huenther c. Neurohormonal d. Hormonal ANS: A Paracrine signaling involves the release of local chemical mediators that are quickly taken up, destroyed, or immobilized, as in the case of insulin and the inhibition of the secretion of glucagon. When cells produce signals that they themselves respond to, autocrine signaling is used. Neurohormonal signaling involves secretion of hormones into the bloodstream by neurosecretory hormones. Hormonal signaling involves specialized endocrine cells that secrete hormone chemicals released by one set of cells that travel through the tissue through the bloodstream to produce a response in other sets of cell s. 9. In cellular metabolism, each enzyme has a high affinity for a: a. Solute b. Substrate c. Receptor d. Ribosome ANS: B Each enzyme has a high affinity for a substrate, a specific substance converted to a product of the reaction. Solutes are small particles that pass through the cell membrane. A receptor is a site on the cell wall that allows transport into the cell. Ribosomes are located inside the cell and are not related to the work of enzymes. Test Bank For: Understanding Pathophysiology 7th Edition By Sue Huenther 10. An athlete runs a marathon, after which his muscles feel fatigued and unable to contract. The athlete asks the nurse why this happened. How should the nurse respond? A deficiency in can cause impaired muscle contraction. a. GTP b. AMP c. ATP d. GMP ANS: C The cell uses ATP for muscle contraction. when it is deficient, impaired muscle contraction results. GTP is involved in cell signaling, not muscle contraction. AMP is not involved in muscle contraction. GMP is not involved in muscle contraction. 11. Which phase of catabolism produces the most ATP? a. Digestion b. Glycolysis c. Oxidation d. Citric acid cycle ANS: D Most of the ATP is generated during the citric acid cycle. Larger molecules are broken down into smaller units during digestion; no ATP is produced during this cycle. Test Bank For: Understanding Pathophysiology 7th Edition By Sue Huenther During glycolysis, two molecules of ATP are produced from each glucose molecule, but the most ATP is produced during the citric acid cycle. Oxidation is part of the glycolysis process and ATP is produced, but more ATP is produced during the citric acid cycle. 12. A nurse is teaching the staff about the three phases of cellular catabolism. Which of the following should the nurse include? a. Digestion, glycolysis and oxidation, and the citric acid cycle b. Diffusion, osmosis, and mediated transport c. S phase, G phase, and M phase d. Metabolic absorption, respiration, and excretion ANS: A Digestion, glycolysis and oxidation, and the citric acid cycle are the three phases of cellular catabolism. Diffusion, osmosis, and mediated transport are parts of the movement of fluids in and out of cells. The S, G, and M phases are phases of cellular division, not catabolism. Metabolic absorption, respiration, and excretion are functions of the cell. 13. A runner has depleted all the oxygen available for muscle energy. Which of the following will facilitate his continued muscle performance? a. Electron -transport chain b. Aerobic glycolysis c. Anaerobic glycolysis d. Oxidative phosphorylation ANS: C Test Bank For: Understanding Pathophysiology 7th Edition By Sue Huenther When no oxygen is available, anaerobic glycolysis occurs. The electron -transport chain is part of the citric acid cycle. Aerobic glycolysis involves the presence of oxygen. Oxidative phosphorylation is the mechanism by which the energy produced from carbohydrates, fats, and proteins is transferred to ATP. It is not part of muscle performance. 14. The faculty member asked the student to identify the appropriate term for the movement of small, electrically uncharged molecules through a semipermeable barrier. Which answer indicates the nursing student understood the teaching? a. Osmosis b. Diffusion c. Hydrostatic pressure d. Active transport ANS: B Diffusion is the movement of a solute molecule from an area of greater solute concentration to an area of lesser solute concentration. Osmosis is the movement of water across a semipermeable membrane from a region of higher water concentration to one of lower concentration. Hydrostatic pressure is the force of fluid against a cell membrane. Within the vascular system, this pressure is the blood pressure. In active transport, molecules move up a concentration gradient. This process requires energy. 15. A nurse is teaching a patient about fluid and electrolytes. Which of the following indicates the teaching was successful regarding elect rolytes? Electrolytes are: a. Small lipid-soluble molecules b. Large protein molecules Test Bank For: Understanding Pathophysiology 7th Edition By Sue Huenther c. Micronutrients used to produce ATP d. Electrically charged molecules ANS: D Electrolytes are electrically charged molecules. Electrolytes are not lipid soluble. Electrolytes are not made up of protein. Electrolytes do not have a role in the production of ATP. 16. A nurse is reading a chart and sees the term oncotic pressure. The nurse recalls that oncotic pressure (colloid osmotic pressure) is determined by: a. Concentration of sodium b. Plasma proteins c. Hydrostatic pressure d. Availability of membrane transporter proteins ANS: B Oncotic pressure is determined by the effect of colloids or plasma proteins. The concentration of sodium plays a role in tonicity. Hydrostatic pressure is the force within a vessel. Membrane transporter proteins are involved in active transport within a concentration gradient. 17. A patient has a body fluid of 300 mOsm/kg. This lab result is measuring: a. Osmolality b. Osmolarity c. Osmotic pressure Test Bank For: Understanding Pathophysiology 7th Edition By Sue Huenther d. Oncotic pressure ANS: A Osmolality measures the number of milliosmoles per kilogram of water, or the concentration of molecules per weight of water. Osmolarity measures the number of milliosmoles per liter of solution, or the concentration of molecules per volume of solution. Osmotic pressure is the amount of hydrostatic pressure required to oppose the osmotic movement of water. Oncotic pressure is from plasma proteins, not body fluids. 18. In teaching a patient with cirrhosis, which information should the nurse include regarding cholesterol? a. Cholesterol decreases the membrane fluidity of the erythrocyte, which reduces its ability to carry oxygen. b. Cholesterol decreases the membrane fluidity of erythrocytes, which reduces its ability to carry hemoglobin. c. Cholesterol increases the membrane fluidity of erythrocytes, which allows binding of excess glucose. d. Cholesterol increases the membrane fluidity of erythrocytes, which prolongs its life span beyond 120 days. ANS: A In cirrhosis, the cholesterol content of the red blood cells plasma membrane increases, causing a decrease in membrane fluidity that seriously affects the cells ability to transport oxygen. In cirrhosis, for example, the cholesterol content of the red blood cells plasma membrane increases, causing a decrease in membrane fluidity that seriously affects the cells ability to transport oxygen, not hemoglobin; the hemoglobin carries the oxygen. Test Bank For: Understanding Pathophysiology 7th Edition By Sue Huenther In cirrhosis, for example, the cholesterol content of the red blood cells plasma membrane increases, causing a decrease in membrane fluidity that seriously affects the cells ability to transport oxygen; it does not bind excess glucose. In cirrhosis, for example, the cholesterol content of the red blood cells plasma membrane increases, causing a decrease in membrane fluidity that seriously affects the cells ability to transport oxygen. It does not prolong the life of the RBC and could decrease it. 19. A nurse is discussing the movement of fluid across the arterial end of capillary membranes into the interstitial fluid surrounding the capillary. Which process of fluid movement is the nurse describing? a. Hydrostatic pressure b. Osmosis c. Diffusion d. Active transport ANS: A Blood reaching the capillary bed has a hydrostatic pressure of 25 to 30 mm Hg, which is sufficient force to push water across the thin capillary membranes into the interstitial space. Osmosis involves the movement of fluid from an area of higher concentration to an area of lower concentration. It does not involve pressure or force. It is related to hydrostatic pressure. Diffusion is the passive movement of a solute from an area of higher solute concentration to an area of lower solute concentration. Active transport involves movement up a concentration gradient. 20. A patient who has diarrhea receives a hypertonic saline solution intravenously to replace the sodium and chloride lost in the stool. What effect will this fluid replacement have on cells? a. Cells will become hydrated. b. Cells will swell or burst. Test Bank For: Understanding Pathophysiology 7th Edition By Sue Huenther c. Cells will shrink. d. Cells will divide. ANS: C The hypertonic saline will cause fluid to leave the intracellular space and enter the vascular space, causing cells to shrink. Intravenous hypertonic solutions lead to cell dehydration. Intravenous hypertonic solutions cause fluid to leave cells; thus, they would shrink, not swell. Intravenous hypertonic solutions do not affect cellular division. 21. A nurse is teaching a patient with diabetes how glucose is transported from the blood to the cell. What type of transport system should the nurse discuss with the patient? a. Active -mediated transport (active transport) b. Active diffusion c. Passive osmosis d. Passive -mediated transport (facilitated diffusion) ANS: D A well-known passive -mediated transport system is that for glucose in erythrocytes (red blood cells). The transport of glucose does not require energy, so active -mediated transport is not correct. The transport of glucose does not require energy, so active diffusion is not correct. Osmosis involves the movement of water. 22. How are potassium and sodium transported across plasma membranes? a. By passive electrolyte channels