(Test Bank) Pharmacology Final Review Test Bank 2022/2023 | Nurs 6011 Pharmacology Final Review

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NURS 6011 Pharmacology Final Review 2020 1. The nurse provides teaching for a patient who will begin taking bosentan [Tracleer] for pulmonary arterial hypertension (PAH). Which statement by the patient indicates a need for further teaching about this medication? a. “I may take this medication with or without food.” b. “I may develop irreversible liver damage while taking this drug.” c. “I should not take cyclosporine while taking this medication.” d. “I will need to have lab tests every month while taking this drug.” ANS: B Liver injury may occur with bosentan but all cases to date have been reversible. The medication may be taken without regard to meals. Patients taking bosentan should not take cyclosporine concurrently. Patients will need to have liver enzymes measured monthly while taking the drug. 2. A patient with a history of heart disease develops pulmonary arterial hypertension (PAH), and the provider is considering prescribing sildenafil [Revatio]. The nurse caring for this patient will perform a careful drug history and notify the provider if the patient is taking which medication? a. A beta blocker b. A calcium channel blocker c. Nitroglycerin d. Warfarin ANS: C Patients taking sildenafil should not take nitroglycerin, since the combination can produce a life - threatening drop in blood pressure. Beta blockers, calcium channel blockers, and warfarin are not contraindicated with sildenafil. 3. A pregnant patient begins active labor at 30 weeks’ gestation. The provider orders dexamethasone 6 mg intramuscularly to be given twice daily for 4 doses. The patient asks the nurse what effect this drug will have on the fetus. The nurse will tell her that the dexamethasone is given to: a. improve cognitive function in the fetus. b. improve fetal neuromotor development. c. increase fetal weight and length. d. increase lung development in the fetus. ANS: D When preterm delivery cannot be prevented, injecting the pregnant patient with glucocorticoids can accelerate fetal lung maturation. Glucocorticoids do not improve cognitive function, neuromotor development, or physical size in the fetus. 4. A nurse counsels a patient who is to begin taking gamma -hydroxybutyrate [Xyrem] for narcolepsy. It is important for the nurse to warn the patient that respiratory depression is a potential risk with concomitant use of: a. alcohol. b. beta blockers. c. caffeine. d. nicotine. ANS: A The nurse should advise the patient to avoid alcohol when taking gamma - hydroxybutyrate, because combining the two increases the risk of respiratory depression. Gamma -hydroxybutyrate has no drug -to-drug interactions with beta blockers, caffeine, or nicotine. 5. A provider has told a parent that a 3-year -old child has a minor ear infection and that an antibiotic would be prescribed in a couple of days if the child’s symptoms worsened. The parent asks the nurse why the child cannot get an antibiotic today. Which response by the nurse is correct? a. “If the eardrum ruptures, we can culture the fluid to determine which antibiotic is best.” b. “Most ear infections are caused by viruses, so antibiotics are not effective.” c. “Most ear infections will resolve on their own without antibiotics.” d. “Your child will develop tolerance to antibiotics if they are prescribed too often.” ANS: C The vast majority of acute otitis media (AOM) episodes resolve without treatment, so unless the child is very ill, observation is the initial choice. Spontaneous rupture of the tympanic membrane can occur, but clinicians do not wait for it to happen to obtain a culture that will guide treatment. About 70% to 90% of AOM episodes are bacterial in origin. Patients do not develop tolerance to antibiotic effects; overuse of antibiotics can lead to resistant organisms. 6. A nurse is teaching a parent about the observation strategy for managing a 3-year -old child’s ear infection. Which statement by the parent indicates understanding of the teaching? a. “I should not give analgesics, because they may mask important symptoms.” b. “I will give ibuprofen or acetaminophen for pain or fever as needed.” c. “I will let my provider know if the symptoms are not better in 1 week.” d. “There is a slight risk of mastoiditis if antibiotic therapy is delayed.” ANS: B Observation is defined as management by symptomatic relief alone for 48 to 72 hours to allow time for AOM to resolve on its own. Parents should be taught to administer analgesics/antipyretics. Providing pain relief does not mask an important symptom. Parents should notify the provider if symptoms worsen or do not improve in 48 to 72 hours. There is no significant difference in the risk of developing mastoiditis. 7. An 18 -month -old child is seen in the clinic with a temperature of 40°C. The child’s parents tell the nurse that the child developed the fever the previous evening and was inconsolable during the night. The provider examines the child and notes a bulging, erythematous tympanic membrane. The nurse will expect to: a. ask the parent to return to the clinic in 2 days to see whether antibiotics need to be started. b. discuss a referral to an ear, nose, and throat specialist for follow -up treatment. c. teach the parent to give analgesics for 3 days while observing for worsening symptoms. d. tell the parent to administer amoxicillin at 45 mg/kg/dose twice daily. ANS: D Patients with severe symptoms of AOM should begin treatment with antibiotics upon diagnosis. For children 6 months to 2 years of age, treatment should begin when the diagnosis is certain, as evidenced by erythema of the tympanic membrane (TM) and distinct discomfort. Amoxicillin 45 mg/kg/dose twice daily is indicated. Observation for 2 days is not recommended for this child, because the diagnosis is certain; therefore, asking the parent to return in 2 days or to give only symptomatic treatment is incorrect. Referral to an ear, nose, and throat (ENT) specialist is not recommended unless the child has recurrent AOM or if treatments repeatedly fail 8. The nurse is administering ear drops to a patient with acute bacterial otitis externa. Which procedure would assist drug penetration into the ear canal? a. Administering refrigerated drops b. Inserting a sponge wick into the ear canal and then administering the drops c. Cleaning out the earwax with a cotton -tipped swab before giving the drops d. Inserting earplugs after administering the drops ANS: B Insertion of a sponge wick can aid delivery of the ear drops to the epithelium of the ear canal. Medication is absorbed into the wick, which delivers the drug to the epithelium. Ear drops should be warmed before administration to prevent dizziness, which may occur with instillation of cold drops. Cerumen should not be removed. Inserting cotton - tipped swabs may damage the epithelium. The use of earplugs may lead to further problems with bacterial otitis externa. 9. A teenaged female patient has begun to develop acne and asks a nurse how to minimize pimple formation. What will the nurse recommend? a. Asking the provider about oral contraceptives b. Cleansing the face gently 2 to 3 times daily c. Eliminating greasy foods from the diet d. Using an abrasive agent to scrub the face ANS: B Gentle cleansing 2 to 3 times a day can reduce surface oiliness and help minimize acne lesions. Oral contraceptives are not first -line treatment for acne. Eliminating greasy foods from the diet does not affect pimple formation. An abrasive agent is not indicated for mild acne. 10. An adolescent patient with moderate acne has begun a regimen consisting of combination clindamycin/benzoyl peroxide [BenzaClin] and tretinoin [Retin -A]. Which statement by the patient indicates understanding of this medication regimen? a. “I should apply the Retin -A immediately after bathing.” b. “I should apply the Retin -A twice daily.” c. “I should augment this therapy with an abrasive soap.” d. “I should use sunscreen every day.” ANS: D Tretinoin increases susceptibility to sunburn, so patients should be warned to apply a sunscreen and wear protective clothing. Before applying Retin -A, the skin should be washed, toweled dry, and allowed to dry fully for 15 to 30 minutes. Retin -A is applied once daily. Abrasive soaps intensify localized reactions to Retin -A and should not be used. 11. 11. 8. A patient will begin initial treatment for severe acne. Which regimen will the nurse expect the provider to order? a. Clindamycin/benzoyl peroxide [BenzaClin] and tretinoin [Retin -A] b. Doxycycline [Vibramycin] and tretinoin [Retin -A] c. Erythromycin [Ery -Tab) and benzoyl peroxide d. Topical clindamycin and isotretinoin [Accutane] ANS: B Oral antibiotics are used for moderate to severe acne and are usually combined with a topical retinoid. Combination clindamycin/benzoyl peroxide and tretinoin are used for mild to moderate acne. Erythromycin can be used as an oral antibiotic but would need to be combined with a topical retinoid. Isotretinoin is used for severe acne that has not responded to other treatments. 12. A 50-year -old patient receives botulinum toxin type A [Botox] injections for the first time on her forehead and around her eyes. One week later, she calls the clinic to report that she is experiencing droopy eyelids. The nurse will tell the patient that this effect: a. is normal and will resolve in a few days. b. may persist for 3 to 6 months but will resolve. c. may progress to cause drooling and dysphagia. d. represents an adverse effect that may be permanent. ANS: B Botox is a neurotoxin that acts on cholinergic neurons to block the release of acetylcholine. Injection into the wrong site or diffusion from the correct site into surrounding tissues can weaken muscles not intended as targets. This patient’s droopy eyelids are an example of t he wrong site being affected. Weakening of muscles can last 3 to 6 months but will resolve. It is incorrect to tell the patient that it is a normal effect or that it will resolve in a matter of days. Drooling and dysphagia are likely when injections are around the mouth. It is not a permanent effect. 13. A patient begins using timolol [Timoptic] to treat primary open -angle glaucoma (POAG). The nurse gives a dose and notes that the patient develops shortness of breath. The nurse assesses the patient and auscultates wheezes in both lungs. The nurse will ask this patient about a history of which condition? a. Asthma b. Atrioventricular heart block c. Pulmonary hypertension d. Sinus bradycardia ANS: A Timolol is a beta blocker and can precipitate bronchoconstriction when absorbed systemically. Patients with asthma will develop shortness of breath and wheezing. These symptoms are not associated with AV block, pulmonary hypertension, or sinus bradycardia. 14. 14. A nursing student asks the nurse to discuss the differences between POAG and angle -closure glaucoma. Which statement by the nurse is correct? a. “Angle -closure glaucoma may be asymptomatic until irreversible damage has occurred.” b. “Both types are more common in African American patients.” c. “Drug therapy is the definitive treatment for angle -closure glaucoma.” d. “Early treatment with prostaglandin analogs can stop the progression of POAG.” ANS: D Prostaglandin analogs are first-line agents for treating POAG, and early treatment can stop the progressi on. Angle -closure glaucoma has a rapid onset of painful symptoms. POAG is more common in African Americans but angle -closure glaucoma is not. Surgery, not drugs, is the definitive treatment for angle -closure glaucoma. 15. 15. A nurse administers timolol [Timoptic] ophthalmic drops to a patient who has glaucoma. The patient reports stinging of the eyes shortly after the drops were administered. What will the nurse do? a. Monitor the patient’s heart rate, respiratory rate, and blood pressure. b. Notify the provider that the patient shows signs of angle -closure glaucoma. c. Reassure the patient that these are localized, reversible effects of the drug. d. Request an order for an antihistamine to treat this allergic response to the drug. ANS: C Local effects of timol ol and other beta blockers are generally minimal, but transient ocular stinging can occur. There is no need to monitor vital signs, because this does not represent a systemic reaction. This is not a sign of angle -closure glaucoma. Antihistamines will not help. 16. A patient has been using latanoprost [Xalatan] ophthalmic drops. The patient tells the nurse, “My eyes used to be greenish -brown, but now they’re brown.” What will the nurse do? a. Reassure the patient that this is a harmless side effect. b. Report this toxic effect to the patient’s provider. c. Tell the patient that this indicates an increased risk of migraine headaches. d. Tell the patient that this effect will reverse when the medication is withdrawn. ANS: A Latanoprost can cause a harmless, heightened brown pigment of the iris that stops when the medication is discontinued but does not regress. It is not a sign of a toxic reaction. It does not indicate an increased risk of developing migraines. It will not reverse. 17. 17. A nurse is teaching a patient who will begin using a fixed -dose preparation of dorzolamide and timolol [Cosopt] for open -angle glaucoma. Which statement by the patient indicates a need for further teaching? a. “Blurred vision, tearing, or eye dryness may occur with this medication.” b. “I may experience a bitter taste in my mouth after instilling these eye drops.” c. “I will need to instill two eye drops 3 times daily in each eye.” d. “If I notice redness in my eyes or eyelids, I should stop using these drops.” ANS: C The fixed -dose preparation of dorzolamide and timolol is given as 1 drop twice daily. Blurred vision, tearing, eye dryness, and a bitter aftertaste are expected side effects. Redness in the eyes or eyelids indicates an allergic conjunctivitis and means that the drops should be discontinued. 18. A patient has had dilation of the eyes with an anticholinergic agent. What will the nurse say when preparing this patient to go home after the examination? a. “Systemic side effects will not occur with this agent.” b. “You may experience an increased heart rate, but this is a harmless side effect.” c. “You may need to wear dark glasses until this medication wears off.” d. “You will be able to read as soon as the exam is completed.” ANS: C Because the agent causes cycloplegia, which paralyzes the iris sphincter, the eyes are unable to respond to bright light, so patients should be advised to wear sunglasses until this effect wears off. Systemic side effects do occur with these agents. Tachycardia is a systemic effect and may indicate toxicity. Mydriasis is an effect of this drug, causing the eye to be unable to focus; patients will have blurred vision until this effect wears off. 19. A patient with severe allergic conjunctivitis who has been using cromolyn ophthalmic drops for 2 days calls the nurse to report persistence of the symptoms. When the nurse explains that it takes several weeks for maximum benefit to occur, the patient asks if there is something else to use in the meantime. The nurse will suggest that the patient discuss which drug with the provider? a. An ophthalmic demulcent b. H1-receptor antagonists c. Glucocorticoid drops d. Ocular decongestants ANS: B Histamine receptor antagonists can be used to provide immediate symptom relief, so until the cromolyn has provided relief, they may be useful for treating symptoms. Demulcents only add moisture to the eye and do not prevent chemical mediators from causing symptoms. Glucocorticoids are used for inflammatory disorders of the eye but are not first - line agents. Ocular decongestants are used to treat redness caused by minor irritants. 20. An older adult patient comes to an ophthalmology clinic complaining of increased difficulty reading in dim light. The provider examines the patient and notes three large yellow deposits under the patient’s cornea. The nurse will expect the provider to order which treatment for this patient? a. High doses of vitamins C and E, beta -carotene, and zinc b. Laser therapy c. Pegaptanib [Macugen] d. Photodynamic therapy ANS: A This patient has three large drusen with minor vision changes, signs of intermediate age-related macular degeneration (ARMD). Patients with intermediate ARMD can significantly reduce their risk of developing advanced ARMD by taking high doses of vitamins C and E, beta -carotene, and zinc. Laser th erapy, pegaptanib, and photodynamic therapy are used to manage wet, or neovascular, ARMD. 21. A patient is about to undergo emergency surgery for acute angle -closure glaucoma. Before surgery, which agent(s) will the nurse expect to administer? (Select all that apply.) a. Acetazolamide b. Brimonidine [Alphagan] c. Mannitol d. Phenylephrine e. Timolol ANS: A, C, E Acetazolamide is used short term, in conjunction with other agents, to produce rapid lowering of IOP in patients with angle -closure glaucoma. Mannitol is an osmot ic agent used in the emergency treatment of acute angle -closure glaucoma. Timolol helps reduce the production of aqueous humor and can be used in emergency treatment of angle - closure glaucoma. Brimonidine is used for long -term therapy for glaucoma. Phenylephrine is an adrenergic agonist used as a mydriatic agent 22. The nurse is reviewing personal knowledge of the medications used in the treatment of open -angle glaucoma. The nurse would be correct to identify which medication(s) as treatment? (Select all that apply.) a. Alpha 2 agonists b. Prostaglandin analogs c. Anticholinergics d. Carbonic anhydrase inhibitors e. Beta blockers ANS: A, B, D, Em The nurse is correct to identify alpha 2 agonists, prostaglandin analogs, carbonic anhydrase inhibitors, and beta blockers as the drugs used in the treatment of open -angle glaucoma. Anticholinergic agents are used to produce mydriasis and cycloplegia to facilitate intraocular examination and intraocular surgery 23. A patient has completed treatment with lindane shampoo for pediculosis, but the infestation has not been eradicated. The patient asks the nurse about repeating the treatment. What will the nurse tell the patient? a. A second treatment may be administered in 2 to 4 weeks. b. Lindane continues to have residual effects for several weeks after treatment. c. Repeat use of this drug may cause serious side effects. d. The patient should ask the prescriber to order lindane cream for a second treatment. ANS: C